MY HEART FITNESS™ CLINICAL EVIDENCE

Clinical Evidence

Built on peer-reviewed science and real-world implementation.

MHF is built on peer-reviewed research, real-world clinical implementation, patent-pending platform development, and a responsible pathway toward future regulated clinical decision support.

Peer-reviewed Publications

The evidence base behind the platform.

Plain-language summaries of published research from Dr. Alter and collaborators on cardiometabolic outcomes, structured exercise dose, and population health.

JACC . 2026

From insight to infrastructure: Managing cardiorespiratory fitness.

Why cardiorespiratory fitness should be treated as a measurable and manageable health indicator-and why healthcare needs the infrastructure to act on it.

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AJCD . 2023

A learning health system for preventive care.

Real-world implementation of an integrated digital program combining exercise, lifestyle education, disease-management support, and continuous patient engagement.

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ANN INTERN MED . 2015

The health risks of prolonged sedentary time.

A systematic review showing that prolonged sedentary time is associated with mortality, cardiovascular disease, diabetes, cancer, and hospitalization-even after accounting for physical activity.

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CAN J CARDIOL . 2011

The gap between cardiac rehabilitation need and capacity.

A population-level analysis examining whether Ontario's cardiovascular risk-reduction programs had enough capacity to serve the patients who could benefit.

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Patent-pending Platform

Proprietary exercise-dose-to-projection methodology.

MHF's platform is patent-pending across its exercise interpretation, projection logic, and reporting framework. The methodology has been refined over years of real-world clinical implementation and is grounded in published cardiometabolic outcomes literature.

Detailed methodology and conversion logic are protected and not publicly disclosed.

  • Patent-pending. Exercise-dose-to-projection methodology.
  • Cardiology-designed. Built by a practicing cardiologist.
  • Population-informed. Grounded in published outcomes research.
  • Implementation-tested. Refined across 3,000+ patients.
  • Reporting-ready. Aggregate dashboards for partners.

Real-world Implementation

8+ years of clinical implementation experience.

MHF was refined through real-world implementation across clinical, community, employer, and research settings, including the operational learning that emerged from the Milton Cardiac Care program founded by Dr. Alter in 2010.

Setting 01

Clinical & cardiology programs

Integrated into a regional cardiology program serving 3,000+ cardiometabolic patients across community and hospital settings.

Setting 02

Employer & benefits

Implementation partnerships exploring engagement, activation, and projected value for organizational populations.

Setting 03

Research & quality improvement

Collaborations supporting validation, reporting frameworks, and evidence generation.

Regulatory Pathway

Building responsibly toward regulated clinical decision support.

MHF is currently operating as a cardiology-designed, educational, population-informed platform in an early implementation and evidence-generation phase. We are building toward regulated clinical decision-support pathways, including FDA and Health Canada SaMD validation.

MHF is not currently marketed as FDA-approved or Health Canada-approved clinical decision support. We are building the evidence, implementation experience, and regulatory strategy required for responsible future clinical use.

Collaborate With Us

Research, regulatory & clinical collaboration opportunities.

We welcome conversations with research institutions, regulatory partners, and clinical groups interested in shaping the evidence base for responsible digital prevention.